Efficacy of a 20:1 CBD:THC cannabis herbal extract for pain and inflammation in dogs following tibial plateau leveling osteotomy

Overall, administration of an oral 20:1 CBD: THC cannabis herbal extract in addition to a standard analgesic protocol did not improve analgesia and limb function following TPLO surgery in dogs. Minor functional benefits may have occurred in the higher CHE dose group, but only on the first day following surgery. Current multimodal peri- and post-operative analgesic practices were effective, irrespective of CHE administration.

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Publication Details

Journal
Frontiers in Veterinary Science
Published
2025-09-29
DOI
https://doi.org/10.3389/fvets.2025.1676779
Primary Topic
Human-Animal Interaction Studies
Type
article
Field-Weighted Citation Impact
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article

Efficacy of a 20:1 CBD:THC cannabis herbal extract for pain and inflammation in dogs following tibial plateau leveling osteotomy

Alan Chicoine, LJ Holmes, K. Romany Pinto, Jane Alcorn et al.
Frontiers in Veterinary Science
Human-Animal Interaction Studies
article

Efficacy of a 20:1 CBD:THC cannabis herbal extract for pain and inflammation in dogs following tibial plateau leveling osteotomy

Alan Chicoine, LJ Holmes, K. Romany Pinto, Jane Alcorn, Ahmed M. Salama, Chloe Lyons, Kira Penney
article en

Abstract

Overall, administration of an oral 20:1 CBD: THC cannabis herbal extract in addition to a standard analgesic protocol did not improve analgesia and limb function following TPLO surgery in dogs. Minor functional benefits may have occurred in the higher CHE dose group, but only on the first day following surgery. Current multimodal peri- and post-operative analgesic practices were effective, irrespective of CHE administration.

Frontiers in Veterinary ScienceVol. 12
University of Saskatchewan (CA)
Openalex Percentile: Top 71%
Human-Animal Interaction Studies
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