The future is in the background: background EEG patterns, not acute seizures, predict epilepsy and neurodevelopmental outcomes in neonatal HIE
In our cohort, EEG background patterns outperformed ictal burden in predicting both neurodevelopmental outcomes and future epilepsy risk. Although background patterns are not directly modifiable, they provide powerful, early markers of brain injury severity, offering clinicians a valuable tool for prognostication and family counseling at a critical juncture in care.
Authors
- Kimberly Amador (ORCID: https://orcid.org/0000-0003-3956-1895)
- Pauline Mouchès (ORCID: https://orcid.org/0000-0002-0304-5584)
- Khorshid Mohammad (ORCID: https://orcid.org/0000-0002-3568-7282)
- Pauline de Jesus
- Nils D. Forkert (ORCID: https://orcid.org/0000-0003-2556-3224)
- Marvin H. Braun
- Kristine Woodward (ORCID: https://orcid.org/0000-0002-2368-0454)
- Michael J. Esser
Institutions
- University of Calgary (CA)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2025-09-29
- DOI
- https://doi.org/10.3389/fped.2025.1560760
- Primary Topic
- Neonatal and fetal brain pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Alberta Children's Hospital Research Institute