Temporal shifts in semen parameters across a major COVID-19 outbreak wave: a retrospective cohort study using epidemiological time-windows

Semen concentration and motility were significantly lower in samples collected during the peak of a major COVID-19 outbreak wave, with parameters returning to pre-outbreak levels in the subsequent 3-month period. Key sperm functional biomarkers, including acrosin activity and DNA integrity, appeared resilient throughout these distinct epidemiological phases.

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Publication Details

Journal
Frontiers in Reproductive Health
Published
2025-09-29
DOI
https://doi.org/10.3389/frph.2025.1691216
Primary Topic
COVID-19 Impact on Reproduction
Type
article
Field-Weighted Citation Impact
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article

Temporal shifts in semen parameters across a major COVID-19 outbreak wave: a retrospective cohort study using epidemiological time-windows

Zhezhuang Xu, Jiayong Zheng, Hai Wang, Xiaoguo Zheng et al.
Frontiers in Reproductive Health
COVID-19 Impact on Reproduction
article

Temporal shifts in semen parameters across a major COVID-19 outbreak wave: a retrospective cohort study using epidemiological time-windows

Zhezhuang Xu, Jiayong Zheng, Hai Wang, Xiaoguo Zheng, Hongyu Pan
article en

Abstract

Semen concentration and motility were significantly lower in samples collected during the peak of a major COVID-19 outbreak wave, with parameters returning to pre-outbreak levels in the subsequent 3-month period. Key sperm functional biomarkers, including acrosin activity and DNA integrity, appeared resilient throughout these distinct epidemiological phases.

Frontiers in Reproductive HealthVol. 7
Wenzhou Medical University (CN), Wenzhou City People's Hospital (CN)
Openalex Percentile: Top 67%
COVID-19 Impact on Reproduction
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