Machine learning-based identification of leptin-associated biomarkers and prognostic prediction models in sepsis

We established leptin-related prognostic models for sepsis using integrated machine learning. TFRC and PILRA may serve as promising biomarkers, offering insights into sepsis heterogeneity and clinical management.

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Publication Details

Journal
Frontiers in Cellular and Infection Microbiology
Published
2025-09-29
DOI
https://doi.org/10.3389/fcimb.2025.1630446
Primary Topic
Single-cell and spatial transcriptomics
Type
article
Field-Weighted Citation Impact
0.00
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article

Machine learning-based identification of leptin-associated biomarkers and prognostic prediction models in sepsis

Qiunan Zuo, Caiyu Jiang, Yi Liao, Xiaoshu Liu et al.
Frontiers in Cellular and Infection Microbiology
Single-cell and spatial transcriptomics
article

Machine learning-based identification of leptin-associated biomarkers and prognostic prediction models in sepsis

Qiunan Zuo, Caiyu Jiang, Yi Liao, Xiaoshu Liu, Liqing Yang, Song Jun-mei
article en

Abstract

We established leptin-related prognostic models for sepsis using integrated machine learning. TFRC and PILRA may serve as promising biomarkers, offering insights into sepsis heterogeneity and clinical management.

Frontiers in Cellular and Infection MicrobiologyVol. 15
University of Electronic Science and Technology of China (CN)
Openalex Percentile: Top 76%
Single-cell and spatial transcriptomics
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