Iatrogenic Cushing’s syndrome induced by topical steroid abuse in a patient with psoriasis: a case report

This case underscores the critical need for clinicians to remain vigilant about the potential systemic adverse effects of topical glucocorticoids, particularly in psoriasis patients, where even minimal concentrations of clobetasol propionate can precipitate ICS. Furthermore, identifying the source of exogenous glucocorticoids in ICS necessitates a thorough review of the patient's medication history, encompassing over-the-counter drugs and supplements. It is important that medication use be guided by specialist consultation and rigorous monitoring, rather than unsupervised self-medication.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-09-29
DOI
https://doi.org/10.3389/fmed.2025.1591869
Citations
1
Primary Topic
Psoriasis: Treatment and Pathogenesis
Type
article
Field-Weighted Citation Impact
0.80

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article

Iatrogenic Cushing’s syndrome induced by topical steroid abuse in a patient with psoriasis: a case report

Shaopeng Du, C. Wang, Jie Sun, Wei Li et al.
1 citations
Frontiers in Medicine
Psoriasis: Treatment and Pathogenesis
0.80
article

Iatrogenic Cushing’s syndrome induced by topical steroid abuse in a patient with psoriasis: a case report

Shaopeng Du, C. Wang, Jie Sun, Wei Li, Jianwei Chen, Shujun Wang, Haiying Zhao
article en
1 citations

Abstract

This case underscores the critical need for clinicians to remain vigilant about the potential systemic adverse effects of topical glucocorticoids, particularly in psoriasis patients, where even minimal concentrations of clobetasol propionate can precipitate ICS. Furthermore, identifying the source of exogenous glucocorticoids in ICS necessitates a thorough review of the patient's medication history, encompassing over-the-counter drugs and supplements. It is important that medication use be guided by specialist consultation and rigorous monitoring, rather than unsupervised self-medication.

Frontiers in MedicineVol. 12
Ningbo Medical Center Lihuili Hospital (CN), Cixian People's Hospital (CN)
Wenzhou Medical University
Openalex Percentile: Top 23%
Psoriasis: Treatment and Pathogenesis
0.80
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Iatrogenic Cushing’s syndrome induced by topical steroid abuse in a patient with psoriasis: a case report — Shaopeng Du, C. Wang, et al. · Frontiers in Medicine (2025) | TGRS Research Map | TGRS