Formation of an auditory sensory representation in posterior striatum emerges during a brief temporal window of associative learning in normal and hearing-impaired gerbils
These changes to the intrinsic and synaptic properties likely support LTP induction <i>in vivo</i> and the strengthening of synapses between auditory inputs and MSNs that facilitate neuronal phase locking. These findings have significant implications for our understanding of striatal resilience to sensory impairments in early life, in addition to establishing a granular understanding of the striatal circuit changes that support reward driven stimulus-response learning.
Authors
- Maged Guirguis (ORCID: https://orcid.org/0000-0003-4700-2698)
- Aaron Tucker
- Daniel J. Murphy (ORCID: https://orcid.org/0000-0001-7759-6576)
- Todd M. Mowery (ORCID: https://orcid.org/0000-0001-7727-6353)
- P. Ashley Wackym (ORCID: https://orcid.org/0000-0002-2904-5072)
- Eran Peci
- Nihaad Paraouty (ORCID: https://orcid.org/0000-0002-7530-5891)
- Jared B. Smith (ORCID: https://orcid.org/0000-0002-0273-4898)
- M. Kiel (ORCID: https://orcid.org/0000-0002-2215-4188)
- Ufuk Utku
- S Chandrasekar
- Jennifer D. Gay
- Nicolas L. Carayannopoulos
- Justin D. Yao (ORCID: https://orcid.org/0000-0001-8762-9044)
- Sean Hong (ORCID: https://orcid.org/0009-0003-9373-263X)
- Evelynne Dangcil
- Jacqueline Nacipucha
- Nikhil Suresh
- Sofia Carayannopoulos
Institutions
- Rutgers, The State University of New Jersey (US)
- Salk Institute for Biological Studies (US)
- Johnson University (US)
Publication Details
- Journal
- Frontiers in Systems Neuroscience
- Published
- 2025-09-29
- DOI
- https://doi.org/10.3389/fnsys.2025.1642595
- Primary Topic
- Neural dynamics and brain function
- Type
- article
- Field-Weighted Citation Impact
- 0.00