Severe course of osmotic demyelination syndrome complicated by recurrent respiratory failure – Case Report

Osmotic demyelination syndrome (ODS) is a non-inflammatory disorder of the central nervous system that arises from osmotic disturbances, particularly related to the rapid correction of chronic ionic imbalances, especially concerning sodium levels.ODS has been shown as an interdisciplinary problem which requires the collaboration of many specialists to achieve successful goals.This case study describes a 46-year-old male patient with a history of chronic alcohol abuse and other underlying health issues, including sodium imbalances.The patient required extensive care, spanning multiple departments -emergency, neurology, psychiatry, and detoxification, over a prolonged hospitalization of 80 days.The patient presented multiple symptoms, including recurrent respiratory disorders requiring intubation.Even with increasing improvements in management, osmotic demyelination syndrome still presents significant therapeutic challenges.Standardized treatment guidelines remain lacking.

Authors

Publication Details

Journal
Journal of Pre-Clinical and Clinical Research
Published
2025-09-26
DOI
https://doi.org/10.26444/jpccr/211303
Primary Topic
Electrolyte and hormonal disorders
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Severe course of osmotic demyelination syndrome complicated by recurrent respiratory failure – Case Report

Klaudia Michalak, Kacper Janowski, Mateusz Wilkowski, Ireneusz Jurczak
Journal of Pre-Clinical and Clinical Research
Electrolyte and hormonal disorders
article

Severe course of osmotic demyelination syndrome complicated by recurrent respiratory failure – Case Report

Klaudia Michalak, Kacper Janowski, Mateusz Wilkowski, Ireneusz Jurczak
article en

Abstract

Osmotic demyelination syndrome (ODS) is a non-inflammatory disorder of the central nervous system that arises from osmotic disturbances, particularly related to the rapid correction of chronic ionic imbalances, especially concerning sodium levels.ODS has been shown as an interdisciplinary problem which requires the collaboration of many specialists to achieve successful goals.This case study describes a 46-year-old male patient with a history of chronic alcohol abuse and other underlying health issues, including sodium imbalances.The patient required extensive care, spanning multiple departments -emergency, neurology, psychiatry, and detoxification, over a prolonged hospitalization of 80 days.The patient presented multiple symptoms, including recurrent respiratory disorders requiring intubation.Even with increasing improvements in management, osmotic demyelination syndrome still presents significant therapeutic challenges.Standardized treatment guidelines remain lacking.

Journal of Pre-Clinical and Clinical ResearchVol. 19(4)
Openalex Percentile: Top 61%
Electrolyte and hormonal disorders
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.