SARS-CoV-2 Infection Alters the Immune Microenvironment in Lung Cancer Patients Undergoing Immunotherapy and Affects Treatment Outcomes
SARS-CoV-2 infection transiently alters the immune landscape in lung cancer patients without compromising ICI efficacy. The sustained elevation of IL-10 and IL-12p70 may contribute to short-term clinical benefits. Monitoring cytokine dynamics could serve as a prognostic tool for predicting ICI response.
Authors
- Guirong Wang (ORCID: https://orcid.org/0000-0001-8907-3393)
- Jinjing Tan (ORCID: https://orcid.org/0000-0003-3534-8376)
- Teng Ma (ORCID: https://orcid.org/0000-0003-1512-8018)
- Panjian Wei (ORCID: https://orcid.org/0000-0001-9678-4361)
- Yanjing Peng
- Meng Gu (ORCID: https://orcid.org/0000-0002-2394-4245)
Institutions
- Beijing Chest Hospital (CN)
Publication Details
- Journal
- Viruses
- Published
- 2025-09-28
- DOI
- https://doi.org/10.3390/v17101314
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00