High‐caloric intake rescues early symptomatic AD‐induced hippocampal neurovascular coupling deficits
Pseudo-continuous arterial spin labeling (pCASL) magnetic resonance imaging (MRI) -based characterization of hippocampal functional hyperemia. Hippocampal functional hyperemia is attenuated in symptomatic Alzheimer's disease (AD) pathology. A high-carbohydrate, high-fat (HCHF) diet transiently restores hippocampal functional hyperemia in symptomatic AD pathology.
Authors
- Greg J. Stanisz (ORCID: https://orcid.org/0000-0002-9488-7612)
- Margaret M. Koletar (ORCID: https://orcid.org/0000-0003-4464-3887)
- JoAnne McLaurin
- Bojana Stefanovic (ORCID: https://orcid.org/0000-0002-8439-7601)
- Aaron Y. Lai (ORCID: https://orcid.org/0000-0001-5188-0034)
- Andrea Trevisiol (ORCID: https://orcid.org/0000-0002-7265-3639)
- Dustin Loren Almanza (ORCID: https://orcid.org/0009-0002-0558-2460)
- Mary Hill
- Jessica A. Ribeiro
Institutions
- Medical University of Lublin (PL)
- Sunnybrook Health Science Centre (CA)
- University of Toronto (CA)
- Sunnybrook Hospital (CA)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1002/alz.70708
- Citations
- 1
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 1.16