Identification and Characterization of Three Novel Biomarkers for Mixed/Cholestatic Drug‐Induced Liver Injury
We identified novel DILI biomarkers that can be used to clinically assess patients with mixed/cholestatic DILI and to differentiate these patients from recovered patients and those with other liver diseases.
Authors
- Naoya Sakamoto (ORCID: https://orcid.org/0000-0003-0061-059X)
- Keiji Tsuji (ORCID: https://orcid.org/0000-0003-4000-835X)
- Yoshiro Saito (ORCID: https://orcid.org/0000-0002-6669-8152)
- Kazuhide Takata (ORCID: https://orcid.org/0000-0002-0255-2904)
- Kosuke Saito (ORCID: https://orcid.org/0000-0002-1035-3454)
- Motonobu Sato
- Kazuhiko Mori (ORCID: https://orcid.org/0000-0003-1353-264X)
- Hajime Takikawa (ORCID: https://orcid.org/0000-0002-6231-6786)
- Ruri Kikura‐Hanajiri (ORCID: https://orcid.org/0000-0002-4251-1664)
- Noriaki Arakawa (ORCID: https://orcid.org/0000-0003-2286-0629)
- Ken Sato (ORCID: https://orcid.org/0000-0002-3202-7983)
- Takayoshi Nishiya
- Mitsuhiko Aiso
- Kazuhiko Takamatsu (ORCID: https://orcid.org/0000-0003-3773-8941)
- Tatehiro Kagawa (ORCID: https://orcid.org/0000-0002-3442-1423)
- Shunji Hirose (ORCID: https://orcid.org/0000-0001-6116-340X)
- Toshio Uraoka (ORCID: https://orcid.org/0000-0002-4425-4331)
- Shotaro Sakisaka (ORCID: https://orcid.org/0000-0002-1231-9874)
- Koji Ogawa
- Takashi Izumi (ORCID: https://orcid.org/0000-0002-4268-1874)
- Nami Mori
- Yasuo Ohno
- Yuji Kumagai
Institutions
- Kihara Institute for Biological Research (JP)
- Tokai University (JP)
- Astellas Pharma (Japan) (JP)
- Teikyo University of Science (JP)
- Gunma University (JP)
- Daiichi Sankyo (Germany) (DE)
- Hokkaido University (JP)
- Fukuoka University (JP)
- Daiichi-Sankyo (Japan) (JP)
- Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital (JP)
- National Institute of Occupational Safety and Health (JP)
- Memorial Foundation (US)
- National Institute of Health Sciences (JP)
- Kitasato Institute Hospital (JP)
- Teikyo University (JP)
Publication Details
- Journal
- Hepatology Research
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1111/hepr.70043
- Primary Topic
- Drug-Induced Hepatotoxicity and Protection
- Type
- article
- Field-Weighted Citation Impact
- 0.00