Transcriptomic and metabolomic analysis of a non-cyp51A mutant azole-resistant Aspergillus fumigatus isolated from Ningxia, China

In conclusion, this study offers new insights and perspectives on the research of non-<i>cyp51A</i> mutation-related resistance mechanisms, utilizing phenotypic experiments, transcriptome sequencing, and metabolite analysis.

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Publication Details

Journal
Frontiers in Microbiology
Published
2025-09-29
DOI
https://doi.org/10.3389/fmicb.2025.1666905
Primary Topic
Antifungal resistance and susceptibility
Type
article
Field-Weighted Citation Impact
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article

Transcriptomic and metabolomic analysis of a non-cyp51A mutant azole-resistant Aspergillus fumigatus isolated from Ningxia, China

Pengtao Wang, Yuting Kang, Wanting Ma, Jia Wei et al.
Frontiers in Microbiology
Antifungal resistance and susceptibility
article

Transcriptomic and metabolomic analysis of a non-cyp51A mutant azole-resistant Aspergillus fumigatus isolated from Ningxia, China

Pengtao Wang, Yuting Kang, Wanting Ma, Jia Wei, Qiujie Li
article en

Abstract

In conclusion, this study offers new insights and perspectives on the research of non-<i>cyp51A</i> mutation-related resistance mechanisms, utilizing phenotypic experiments, transcriptome sequencing, and metabolite analysis.

Frontiers in MicrobiologyVol. 16
Ningxia Medical University (CN)
Openalex Percentile: Top 68%
Antifungal resistance and susceptibility
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