Astrocyte-derived stanniocalcin-1 orchestrates epileptogenesis through NF-κB-dependent neuroinflammation
This study reveals the molecular mechanism by which astrocyte-derived STC1 promotes TLE-associated neuroinflammation and neuronal injury through activation of the NF-κB signaling pathway, elucidating the crucial role of the astrocyte-STC1-NF-κB axis in epileptogenesis.
Authors
- Qi Song (ORCID: https://orcid.org/0000-0002-1167-871X)
- Xiaofei Guan (ORCID: https://orcid.org/0000-0002-7100-2949)
- Kexin Li (ORCID: https://orcid.org/0009-0001-7193-0534)
- Weimin Wang (ORCID: https://orcid.org/0000-0002-4789-6399)
- Hong Chen (ORCID: https://orcid.org/0000-0001-8054-7417)
Institutions
- Heilongjiang University of Chinese Medicine (CN)
- First Affiliated Hospital of Heilongjiang University of Chinese Medicine (CN)
Publication Details
- Journal
- Cell Cycle
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1080/15384101.2025.2566293
- Primary Topic
- Biochemical effects in animals
- Type
- article
- Field-Weighted Citation Impact
- 0.00