Transcriptomic and Metabolomic Mechanism of Ibuprofen, Chondroitin Sulfate, and Vitamins With Minerals Tablets (21) for Kashin–Beck Disease Treatment
The combination of ibuprofen, chondroitin sulfate, and vitamins with minerals tablets (21) may alleviate KBD through modulation of key genes (GDNF, BDNF, CCL2, VEGFA, and PPARG) and glutamine-related metabolic pathways.
Authors
- Cuiyan Wu (ORCID: https://orcid.org/0000-0001-9824-3411)
- Hui Niu (ORCID: https://orcid.org/0000-0003-1808-8066)
- Zhengjun Yang (ORCID: https://orcid.org/0009-0008-6399-0829)
- Xingxing Deng (ORCID: https://orcid.org/0000-0001-5597-2470)
- Yijun Zhao
- Huan Liu (ORCID: https://orcid.org/0009-0005-6103-2115)
- Qian Zhang (ORCID: https://orcid.org/0000-0002-3880-2020)
- Xiaodong Yang (ORCID: https://orcid.org/0000-0002-4066-7788)
- Jinfeng Wen (ORCID: https://orcid.org/0000-0002-5756-5585)
- Naren Gaowa
Institutions
- National Health and Family Planning Commission (CN)
- Xian Center for Disease Control and Prevention (CN)
- Dazhou Central Hospital (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Rapid Communications in Mass Spectrometry
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1002/rcm.10130
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00