Multistep Synthesis and Structural Analysis of a BODIPY-Quinoline Compound

This article describes the design, synthesis, purification and characterization of a new BODIPY-quinoline compound (6). The molecular design strategy is based on the placement of azido substituents at the 3 and 5 positions of the BODIPY skeleton, preparation of propargyl-quinoline compound (5) and the click reaction between distyryl-BODIPY (4) and propargyl-quinoline (5). The structures of all the new compounds were confirmed by MALDI-MS, 1H and 13C NMR spectroscopic techniques. This combination allows the formation of binding sites for metal ions. Thus, the BODIPY-quinoline compound presented in this study is promising for the development of novel fluorescent sensors. The presented synthetic strategy can also be used to synthesize other BODIPY derivatives needed for various applications.