CONTACTLESS BIOFABRICATION APPROACHES FOR TISSUE MODELLING AND REGENERATION

This talk will provide an overview of the activities of the Field-Assisted Biofabrication (FAB) team, which is developing innovative strategies for tissue regeneration and modeling of complex multicellular systems. The team uses extrinsic fields - such as light, acoustic, magnetic and hydrodynamic waves - to spatially assemble cells, aggregates, organoids and extracellular matrices in a controlled and programmable manner. One of the team's key innovations is the enhancement of local cell density through sound-assisted assembly, which enables the creation of reproducible and morphologically relevant tissue constructs. These include spatially organized vasculature, nerve ingrowth associated with low back pain, and 3D mineralized constructs, paving the way for more predictive and human-relevant drug discovery and regenerative therapies.