Tumor Tissue Microbiota in Colorectal Cancer: PCR Profile of FFPE Blocks in Associations with Metastatic Status
PCR-based profiling of FFPE CRC tumors is feasible and reveals hypothesis-generating patterns. Signals linking <i>F. nucleatum</i> to metastatic CRC and <i>Acinetobacter</i> spp. to non-metastatic disease merit validation in larger cohorts; tumor-tissue microbiome features may complement clinicopathological assessment.
Authors
- Nikolay K. Sadykhov (ORCID: https://orcid.org/0000-0002-3800-1506)
- Nikolay K. Shakhpazyan (ORCID: https://orcid.org/0000-0003-3386-7746)
- A.I. Mikhalev (ORCID: https://orcid.org/0000-0002-9463-8229)
- Л.М. Михалева (ORCID: https://orcid.org/0000-0003-2052-914X)
- Z.V. Gioeva (ORCID: https://orcid.org/0000-0002-5456-8692)
- A.L. Bedzhanyan (ORCID: https://orcid.org/0000-0002-4377-0035)
- Konstantin Midiber (ORCID: https://orcid.org/0000-0002-1426-968X)
- Anton S. Buchaka (ORCID: https://orcid.org/0000-0003-3580-1492)
Institutions
- Peoples' Friendship University of Russia (RU)
- Pirogov Russian National Research Medical University (RU)
- State Scientific Center of Coloproctology (RU)
- Research Institute of Human Morphology (RU)
Publication Details
- Journal
- Cells
- Published
- 2025-09-27
- DOI
- https://doi.org/10.3390/cells14191508
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.81