<scp>SIRT1</scp> Expression in Human Gastrointestinal Tumors and Its Clinical Significance
SIRT1 expression in gastrointestinal tumors is tissue-specific (upregulated in GC, downregulated in colorectal cancer). Its expression level is closely associated with malignant progression and patient prognosis, and it may be involved in the modulation of the tumor immune microenvironment. SIRT1 shows promise as a potential diagnostic biomarker and therapeutic target for gastrointestinal cancers.
Authors
- Xinyi Li (ORCID: https://orcid.org/0000-0002-1599-3944)
- Wenhong Deng (ORCID: https://orcid.org/0000-0002-2921-2707)
- Wenxuan Liu (ORCID: https://orcid.org/0000-0002-8459-0241)
Institutions
- Anhui Medical University (CN)
- Wuhan University (CN)
- Renmin Hospital of Wuhan University (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1002/cam4.71217
- Primary Topic
- Sirtuins and Resveratrol in Medicine
- Type
- article
- Field-Weighted Citation Impact
- 0.00