LncRNA LBX2-AS1 exacerbates LPS-induced stress on periodontal ligament cells by activating the TLR2 signaling pathway through miR-654-3p
Upregulation of LBX2-AS1 has the potential to be a marker for the development of periodontitis. miR-654-3p mediates the impact of LBX2-AS1 on LPS-stimulated inflammatory responses and cellular damage in PDLCs <i>via</i> the TLR2/Myd88/NF-κB signaling pathway.
Authors
- Fang Liu (ORCID: https://orcid.org/0000-0003-1121-3004)
- Rongxiu Zhang
- Liang Liu (ORCID: https://orcid.org/0000-0002-6477-254X)
- Wenrui Wang (ORCID: https://orcid.org/0000-0002-7918-3318)
- Cheng Qian (ORCID: https://orcid.org/0000-0001-8772-2871)
- Li Xu (ORCID: https://orcid.org/0009-0003-6940-3262)
Institutions
- Bengbu Medical College (CN)
- First Affiliated Hospital of Bengbu Medical College (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1080/07853890.2025.2554931
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00