Diagnosis and Therapy of Soft Tissue Sarcomas: Spanish Group for Research in Sarcomas (GEIS) Guidelines
Soft tissue sarcomas (STSs) are a rare and highly heterogeneous group of tumours originating from mesenchymal cells, characterized by significant clinical and biological diversity. Due to this complexity, STSs present considerable challenges in both diagnosis and treatment, requiring an expert, multidisciplinary, and coordinated approach. To address these challenges, a multidisciplinary team of experts from the Spanish Group for Research in Sarcomas (GEIS) has developed a comprehensive, evidence-based consensus guideline that incorporates the latest advancements in biology, imaging techniques, and treatment options. The primary objective of this guideline is to provide clear and practical, up-to-date recommendations addressing the key questions that arise in the management of STSs. This approach aims to support therapeutic decision-making, enhance overall patient management, and ultimately improve clinical outcomes for patients affected by STSs. Key recommendations include the use of MRI as the preferred imaging modality prior to biopsy and ensuring that all patients are referred to specialised sarcoma centres with a multidisciplinary team for diagnosis and treatment.
Authors
- Robert Díaz Beveridge (ORCID: https://orcid.org/0000-0003-3719-7014)
- Ana Sebio (ORCID: https://orcid.org/0000-0003-3333-2370)
- José Manuel Asencio (ORCID: https://orcid.org/0000-0002-7533-5513)
- J. Viñals (ORCID: https://orcid.org/0000-0002-7212-039X)
- Javier Martínez‐Trufero (ORCID: https://orcid.org/0000-0002-0997-2573)
- Javier Martín‐Broto (ORCID: https://orcid.org/0000-0001-7350-6916)
- E. Collado
- Enrique de Álava (ORCID: https://orcid.org/0000-0001-8400-046X)
- José Antonio Narváez (ORCID: https://orcid.org/0000-0003-1898-1225)
- Claudia Valverde-Morales
- Xavier García del Muro (ORCID: https://orcid.org/0000-0001-5571-2847)
- R. Vergés
- Rosa Álvarez (ORCID: https://orcid.org/0000-0003-0935-8298)
- Andrés Redondo (ORCID: https://orcid.org/0000-0002-7257-5642)
- Gloria Marquina (ORCID: https://orcid.org/0000-0002-8961-9787)
- María Ángeles Vaz Salgado (ORCID: https://orcid.org/0000-0002-5913-9002)
- Isidro Gracia Alegría (ORCID: https://orcid.org/0000-0002-9743-4184)
- M. Carmen Gómez-Mateo (ORCID: https://orcid.org/0000-0002-0990-7480)
Institutions
- Universitat Autònoma de Barcelona (ES)
- Instituto Cajal (ES)
- Hospital Universitario La Paz (ES)
- Hospital de Sant Pau (ES)
- Bellvitge University Hospital (ES)
- Hospital General Universitario Gregorio Marañón (ES)
- Hospital Clínico San Carlos (ES)
- Hospital Universitari i Politècnic La Fe (ES)
- Hospital Clínico Universitario de Valencia (ES)
- Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (ES)
- Institut Català de Traumatologia i Medicina de l'Esport (ES)
- Hospital Universitario Miguel Servet (ES)
- Vall d'Hebron Hospital Universitari (ES)
- Hospital Universitario Fundación Jiménez Díaz (ES)
- Instituto de Biomedicina de Sevilla (ES)
- Fundación General (ES)
- Hospital Universitario Virgen del Rocío (ES)
- Hospital Universitario Ramón y Cajal (ES)
- Universidad de Sevilla (ES)
Publication Details
- Journal
- Cancers
- Published
- 2025-09-29
- DOI
- https://doi.org/10.3390/cancers17193158
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00