Predictive value of nasopharyngeal microbiota for necrosis after re-irradiation in recurrent nasopharyngeal carcinoma
Nasopharyngeal microbial diversity prior to re-irradiation was significantly higher in the necrosis group. Our predictive model, integrating clinical and microbial features, demonstrated strong performance in predicting PRNN and offers a promising tool for early intervention and prevention strategies.
Authors
- Yan‐Feng Ouyang
- Kai Wen (ORCID: https://orcid.org/0000-0002-4039-4353)
- Ming‐Yuan Chen (ORCID: https://orcid.org/0000-0003-4793-0902)
- Ze-Rong Huang
- Rui You (ORCID: https://orcid.org/0000-0001-9362-8144)
- Yi-Jun Hua
- You‐Ping Liu (ORCID: https://orcid.org/0000-0003-0738-3334)
- Xiong Zou (ORCID: https://orcid.org/0000-0002-4524-8750)
- Yong‐Long Liu
- Wenbin Wu (ORCID: https://orcid.org/0009-0008-5101-2286)
- Zi-Han Qin
Institutions
- Sun Yat-sen University (CN)
- Fifth Affiliated Hospital of Sun Yat-sen University (CN)
- Sun Yat-sen University Cancer Center (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1186/s12885-025-14842-1
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Sun Yat-sen University
- Wu Jieping Medical Foundation