Case report: metachronous male metastatic breast and colon cancer in a BRCA2 mutation carrier

This case highlights the importance of genetic testing, vigilance for second primary malignancies in BRCA2 carriers, and the value of multidisciplinary care for MBC patients. The co-occurrence of these malignancies in a male BRCA2 carrier is rare and underscores the need for broader surveillance in such patients.

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Publication Details

Journal
Discover Oncology
Published
2025-09-29
DOI
https://doi.org/10.1007/s12672-025-03555-3
Primary Topic
BRCA gene mutations in cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Case report: metachronous male metastatic breast and colon cancer in a BRCA2 mutation carrier

Christos Sotiriou, Emiliana Larionesi, Oana-Nicoleta Pilet
Discover Oncology
BRCA gene mutations in cancer
article

Case report: metachronous male metastatic breast and colon cancer in a BRCA2 mutation carrier

Christos Sotiriou, Emiliana Larionesi, Oana-Nicoleta Pilet
article en

Abstract

This case highlights the importance of genetic testing, vigilance for second primary malignancies in BRCA2 carriers, and the value of multidisciplinary care for MBC patients. The co-occurrence of these malignancies in a male BRCA2 carrier is rare and underscores the need for broader surveillance in such patients.

Discover OncologyVol. 16(1)
Université Libre de Bruxelles (BE), Institut Jules Bordet (BE), Centre Hospitalier de Wallonie Picarde (BE)
Openalex Percentile: Top 71%
BRCA gene mutations in cancer
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