Pharmacological inhibition of NMDA receptors reduces migration and viability in triple-negative inflammatory breast cancer cell lines
This study provides the first evidence linking NMDARs to IBC progression. Elevated expression and inhibition-sensitive aggressive phenotypes suggest NMDARs as potential biomarkers and therapeutic targets in IBC.
Authors
- Carmen S. Maldonado-Vlaar
- Esther A. Peterson (ORCID: https://orcid.org/0000-0001-7497-0980)
- Laura L. Mendez‐Santacruz (ORCID: https://orcid.org/0009-0004-7205-2122)
- Xavier Bittman-Soto (ORCID: https://orcid.org/0000-0002-8417-5400)
- Alexie Molina-Nieves
Institutions
- University of Puerto Rico, Medical Sciences Campus (PR)
- University of Puerto Rico at Río Piedras (PR)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1007/s12672-025-03604-x
- Primary Topic
- Neuroscience and Neuropharmacology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00