Multifocal Biliary Adenoma Involving the Gallbladder and Common Bile Duct Presenting With Obstructive Jaundice: A Case Report

Biliary adenomas are rare neoplastic processes of the gallbladder and extrahepatic biliary tree that are pre-malignant. These tumors infrequently present with obstructive jaundice, which is more suggestive of underlying invasive malignancy. Here, we present a case of multifocal biliary adenoma without invasive cancer in a 70-year-old man who presented with jaundice. Initial laboratory results and imaging suggested a malignant process, prompting surgical resection. Intraoperative findings and histopathologic examination revealed a multifocal tubulovillous adenoma involving the gallbladder and distal common bile duct. The patient ultimately underwent a curative pancreatoduodenectomy procedure. This case demonstrates multifocal biliary adenoma presenting as jaundice without underlying malignancy. Surgical treatment is necessary to relieve symptoms and prevent the progression to carcinoma.

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Publication Details

Journal
Cureus
Published
2025-09-29
DOI
https://doi.org/10.7759/cureus.93487
Primary Topic
Cholangiocarcinoma and Gallbladder Cancer Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Multifocal Biliary Adenoma Involving the Gallbladder and Common Bile Duct Presenting With Obstructive Jaundice: A Case Report

Iván Salido-Guadarrama, Luis Brandi, Tyler Mouw, Mohamad Sidani et al.
Cureus
Cholangiocarcinoma and Gallbladder Cancer Studies
article

Multifocal Biliary Adenoma Involving the Gallbladder and Common Bile Duct Presenting With Obstructive Jaundice: A Case Report

Iván Salido-Guadarrama, Luis Brandi, Tyler Mouw, Mohamad Sidani, Edwin Onkendi, Kanak Das
article en

Abstract

Biliary adenomas are rare neoplastic processes of the gallbladder and extrahepatic biliary tree that are pre-malignant. These tumors infrequently present with obstructive jaundice, which is more suggestive of underlying invasive malignancy. Here, we present a case of multifocal biliary adenoma without invasive cancer in a 70-year-old man who presented with jaundice. Initial laboratory results and imaging suggested a malignant process, prompting surgical resection. Intraoperative findings and histopathologic examination revealed a multifocal tubulovillous adenoma involving the gallbladder and distal common bile duct. The patient ultimately underwent a curative pancreatoduodenectomy procedure. This case demonstrates multifocal biliary adenoma presenting as jaundice without underlying malignancy. Surgical treatment is necessary to relieve symptoms and prevent the progression to carcinoma.

CureusVol. 17(9)
Texas Tech University (US), Texas Tech University Health Sciences Center (US)
Openalex Percentile: Top 57%
Cholangiocarcinoma and Gallbladder Cancer Studies
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