HOXB13 affects the cancer stem cell characteristics of nasopharyngeal carcinoma by regulating the Wnt/β-catenin/SOX2 pathway
This study demonstrates that HOXB13 facilitates the malignant progression of NPC by regulating the Wnt/β-catenin/SOX2 signaling pathway, suggesting HOXB13 as a potential therapeutic and diagnostic target for NPC, thereby offering a new strategy to improve patient prognosis.
Authors
- Xia Li (ORCID: https://orcid.org/0000-0001-9141-2569)
- Ying Xu (ORCID: https://orcid.org/0009-0000-9279-9224)
Institutions
- Changzhou No.2 People's Hospital (CN)
Publication Details
- Journal
- Hereditas
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1186/s41065-025-00549-7
- Primary Topic
- Cancer-related gene regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00