Use of the BIOFIRE® FILMARRAY® Pneumonia plus Panel to characterize the etiology of lower respiratory tract infections among hospitalized patients in Southern Province, Sri Lanka
Our findings suggest that patients with LRTI in Southern Province, Sri Lanka have a high prevalence of gram-negative bacteria and antibacterial resistance in their sputum samples. However, it remains difficult to differentiate isolates that are colonizers not leading to disease versus the true cause of infection via the use of the BIOFIRE<sup>®</sup> FILMARRAY<sup>®</sup> Pneumonia plus Panel on sputum samples.
Authors
- Christopher W. Woods (ORCID: https://orcid.org/0000-0001-7240-2453)
- Champica K. Bodinayake (ORCID: https://orcid.org/0000-0003-1339-1883)
- Madureka Premamali (ORCID: https://orcid.org/0000-0001-5488-8293)
- Truls Østbye (ORCID: https://orcid.org/0000-0002-0662-7440)
- Sky Vanderburg (ORCID: https://orcid.org/0000-0001-8855-3555)
- Jack Anderson
- C. L. Fonseka (ORCID: https://orcid.org/0000-0003-3364-6257)
- Saumya Wickramasinghe (ORCID: https://orcid.org/0000-0001-7376-6849)
- Robert Rolfe (ORCID: https://orcid.org/0000-0001-9181-4023)
- L. Gayani Tillekeratne (ORCID: https://orcid.org/0000-0001-6012-7271)
- Gaya B. Wijayaratne (ORCID: https://orcid.org/0000-0002-8330-3597)
- Lana Abusalem (ORCID: https://orcid.org/0000-0003-1591-9725)
- D. L. B. Piyasiri (ORCID: https://orcid.org/0000-0002-4660-311X)
- Bradly P. Nicholson (ORCID: https://orcid.org/0000-0001-9517-3876)
- Ruvini Kurukulasooriya (ORCID: https://orcid.org/0000-0002-9783-4313)
- Armstrong Obale (ORCID: https://orcid.org/0009-0006-5804-5377)
- Ajith Nagahawatte (ORCID: https://orcid.org/0000-0001-6481-0203)
- U.H.B.Y. Dilshan
- Zachary A. Weishampel
Institutions
- University of Ruhuna (LK)
- Duke University (US)
- University of California, San Francisco (US)
- National Hospital of Sri Lanka (LK)
- Monterey County Health Department (US)
- Duke Institute for Health Innovation (US)
- Durham VA Medical Center (US)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1186/s12879-025-11562-6
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- BioFire Diagnostics
- University of Ruhuna
- National Institutes of Health
- Fogarty International Center