Clinical value of metagenomic next-generation sequencing in diagnosis of Coxiella burnetii infection
Q fever is a disseminated infectious disease that deserves attention for its nonspecific clinical symptoms. mNGS emerges as a powerful novel tool for pathogen detection, demonstrating significant value in diagnosing Q fever, particularly in where conventional serological and PCR testing is unavailable or inconclusive.
Authors
- Jinyu Xia (ORCID: https://orcid.org/0000-0001-6583-5381)
- Chaohui Zhao (ORCID: https://orcid.org/0000-0001-6474-5843)
- Ziliang Lin
- Xi Liu (ORCID: https://orcid.org/0000-0002-1484-0233)
- Xinghua Li (ORCID: https://orcid.org/0000-0002-3275-2755)
- Huili Chen (ORCID: https://orcid.org/0000-0003-4464-4628)
- Yuting Luo (ORCID: https://orcid.org/0000-0002-7647-0549)
Institutions
- Sun Yat-sen University (CN)
- Fifth Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1186/s12879-025-11581-3
- Primary Topic
- Vector-borne infectious diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Basic and Applied Basic Research Foundation of Guangdong Province