Detection of nocturnal epileptic seizures using a wearable armband: A deep learning approach combining accelerometry and photoplethysmography signals

Our two-step approach enables accurate, long-term detection of severe nocturnal seizures in home settings. The wearable system provides a practical solution for continuous monitoring and real-time alerts, thus potentially reducing SUDEP risk and improving patient safety, fulfilling an urgent unmet need in epilepsy care. Furthermore, by enabling long-term home monitoring, this system may help assess the relationship between seizure events and lifestyle-related triggers such as sleep deprivation, stress, physical exertion, or alcohol consumption, thereby supporting the development of personalized preventive strategies.