Risk factors for scoliosis progression in children with idiopathic short stature on growth hormone therapy

(1) Scoliosis developing in children with idiopathic short stature (ISS) receiving growth hormone (GH) therapy predominantly manifests as mild curvature. (2) If scoliosis develops during GH therapy, continued treatment may increase the risk of scoliosis progression. (3) Patients with smaller initial Cobb Angles are at higher risk of progression, necessitating closer clinical monitoring for this subgroup.