Detection of probable hantavirus infections in clinically suspected dengue patients in a tertiary care hospital in Sri Lanka

The putative 5.1% hantavirus seropositivity rate among clinically suspected dengue patients suggests that hantavirus should be considered in differential diagnoses. Although no hantavirus RNA was detected, the presence of IgM antibodies and negativity to other potential infections indicates a potential recent infection or probable cases. The study highlights the challenge of diagnosing hantavirus due to its similar presentation to dengue fever and the need for improved diagnostic testing. Early diagnosis and tailored management can improve patient outcomes and guide public health responses. Further studies and expanded diagnostic capabilities are recommended to better understand hantavirus prevalence and to improve clinical care for affected patients.