Conversion and upgrading of syringate by Acinetobacter baylyi ADP1
In this study, we discovered a previously unknown activity of syringate conversion in A. baylyi ADP1. By adjusting the expression level of vanAB, syringate can be directed either into gallate or 3MGA, which could be further converted into PDC through the heterologous expression of galA. Our results further highlight the potential and versatility of A. baylyi ADP1 for the conversion and upgrading of lignin-related aromatic compounds.
Authors
- Suvi Santala (ORCID: https://orcid.org/0000-0002-0047-5319)
- Johanna Maarit Koivisto (ORCID: https://orcid.org/0000-0002-7553-1434)
- Elena Efimova
- Heidi Tuomela
Institutions
- Tampere University of Applied Sciences (FI)
- Tampere University (FI)
- Tampere University (FI)
Publication Details
- Journal
- Microbial Cell Factories
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1186/s12934-025-02839-1
- Primary Topic
- Lignin and Wood Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Novo Nordisk
- Novo Nordisk Fonden