Exploring the U-shaped nonlinear relationship of CHG index with metabolic syndrome and mortality risks in metabolic syndrome patients

The CHG index has a substantial U-shaped nonlinear association with the incidence of MetS and the risk of all-cause and cardiovascular death in patients with MetS. Previous interventions have focused primarily on high-risk extremes, but the findings of this study suggest that patients with low CHG levels should also be included in monitoring. Future prospective studies are needed to validate these findings and explore their potential clinical applications in managing MetS patients.