Development of a prediction model for lower limb deformity in patients with hereditary multiple exostoses based on interpretable models and nomogram

ALB, GLB, and PA are independent predictors of genu valgum in HME patients three months later, while GLB, PA, and UA are independent predictors of ankle valgus. The interpretable RF model and constructed nomogram in this study enable clinicians to assess the risk of lower limb deformities in HME patients as early as possible, benefiting more patients.

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Publication Details

Journal
BMC Medical Informatics and Decision Making
Published
2025-09-29
DOI
https://doi.org/10.1186/s12911-025-03196-0
Primary Topic
Bone Tumor Diagnosis and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Development of a prediction model for lower limb deformity in patients with hereditary multiple exostoses based on interpretable models and nomogram

Ling He, Wencai Li, Rongbin Lu, Jun Li et al.
BMC Medical Informatics and Decision Making
Bone Tumor Diagnosis and Treatments
article

Development of a prediction model for lower limb deformity in patients with hereditary multiple exostoses based on interpretable models and nomogram

Ling He, Wencai Li, Rongbin Lu, Jun Li, Junjie Liu, Zhao Huang, Xiaofei Ding, Yonghui Lao
article en

Abstract

ALB, GLB, and PA are independent predictors of genu valgum in HME patients three months later, while GLB, PA, and UA are independent predictors of ankle valgus. The interpretable RF model and constructed nomogram in this study enable clinicians to assess the risk of lower limb deformities in HME patients as early as possible, benefiting more patients.

BMC Medical Informatics and Decision MakingVol. 25(1)
Guangxi Medical University (CN), First Affiliated Hospital of GuangXi Medical University (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 61%
Bone Tumor Diagnosis and Treatments
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Development of a prediction model for lower limb deformity in patients with hereditary multiple exostoses based on interpretable models and nomogram — Ling He, Wencai Li, et al. · BMC Medical Informatics and Decision Making (2025) | TGRS Research Map | TGRS