Investigating the effect of tenuigenin on LPS-induced HPMEC dysfunction by inhibiting SRC activation based on network pharmacology and molecular docking
Tenuigenin alleviates LPS-induced injury and dysfunction of HPMECs by targeting the SRC pathway, providing a target for managing adult pneumonia.
Authors
- Jing Han (ORCID: https://orcid.org/0000-0001-5605-1868)
- Jinchun Wang (ORCID: https://orcid.org/0000-0001-6174-5872)
- Hao Pan (ORCID: https://orcid.org/0009-0007-8325-7141)
- Jingchao Chen (ORCID: https://orcid.org/0000-0002-6978-497X)
- Ma Wan (ORCID: https://orcid.org/0000-0002-4215-2614)
Institutions
- Changchun University of Chinese Medicine (CN)
- The Affiliated Hospital to Changchun University of Chinese Medicine (CN)
Publication Details
- Journal
- Hereditas
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1186/s41065-025-00574-6
- Primary Topic
- Sphingolipid Metabolism and Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00