Implications of coexisting neural antibodies with glial fibrillary acidic protein autoimmunity: a single center retrospective cohort study
Patients with anti-GFAP antibodies and concurrent other neuro-antibodies exhibited different clinical features compared to non-overlapping cases. We suggest that in the presence of coexisting neuronal surface antibodies, these specific neuro-antibodies were predominant in clinical manifestations and prognosis, rather than the anti-GFAP antibody, especially when in a relatively high titer.
Authors
- Yongming Wu (ORCID: https://orcid.org/0000-0003-2558-675X)
- Xiumei Wei (ORCID: https://orcid.org/0000-0003-2748-1222)
- Shengnan Wang (ORCID: https://orcid.org/0000-0003-4941-4071)
- Bingbing Li (ORCID: https://orcid.org/0000-0002-9224-2685)
- Guanghui Liu (ORCID: https://orcid.org/0000-0002-3760-0785)
- Suyue Pan (ORCID: https://orcid.org/0000-0003-2744-1984)
- Dongmei Wang (ORCID: https://orcid.org/0000-0002-9230-7530)
- Sanming Jie
Institutions
- Nanfang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- BMC Neurology
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1186/s12883-025-04439-3
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Southern Medical University
- Nanfang Hospital