Updates in HER2 (ERBB2)-Mutant Metastatic Non-small Cell Lung Cancer Treatment:Small Population, Big Unmet Need

Small Population, Big Unmet NeedThe FDA has now approved zongertinib, a kinase inhibitor indicated for the treatment of adult patients with unresectable or metastatic non-squamous NSCLC whose tumors have HER2 (ERBB2) tyrosine kinase domain activating mutations, as detected by an FDA-approved test, and who have received prior systemic therapy.*For U.S. Healthcare Professionals, please see full Prescribing Information.

Authors

Institutions

Publication Details

Published
2025-09-29
DOI
https://doi.org/10.33590/oncolamj/pzlg8562
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Updates in HER2 (ERBB2)-Mutant Metastatic Non-small Cell Lung Cancer Treatment:Small Population, Big Unmet Need

European Medical Journal
Lung Cancer Treatments and Mutations
article

Updates in HER2 (ERBB2)-Mutant Metastatic Non-small Cell Lung Cancer Treatment:Small Population, Big Unmet Need

European Medical Journal
article en

Abstract

Small Population, Big Unmet NeedThe FDA has now approved zongertinib, a kinase inhibitor indicated for the treatment of adult patients with unresectable or metastatic non-squamous NSCLC whose tumors have HER2 (ERBB2) tyrosine kinase domain activating mutations, as detected by an FDA-approved test, and who have received prior systemic therapy.*For U.S. Healthcare Professionals, please see full Prescribing Information.

European Bioinformatics Institute (GB)
Openalex Percentile: Top 61%
Lung Cancer Treatments and Mutations
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Updates in HER2 (ERBB2)-Mutant Metastatic Non-small Cell Lung Cancer Treatment:Small Population, Big Unmet Need — European Medical Journal · (2025) | TGRS Research Map | TGRS