Oral bowel cleansers and ischemic colitis risk: A real-world disproportionality analysis
To our knowledge, this is one of the largest pharmacovigilance analyses exploring ischemic colitis associated with bowel preparation agents. The findings raise concerns about the presumed safety of PEG and reveal a strong disproportionality signal for bisacodyl. These results highlight the need for individualized bowel preparation strategies, especially in elderly patients with comorbidities.
Authors
- Xuehong Wang (ORCID: https://orcid.org/0000-0001-7251-9643)
- Yuqian Zhou (ORCID: https://orcid.org/0000-0002-8168-3952)
- Min Luo (ORCID: https://orcid.org/0000-0001-7570-2507)
- Wenyu Li (ORCID: https://orcid.org/0000-0001-5914-703X)
Institutions
- Central South University (CN)
- Second Xiangya Hospital of Central South University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1371/journal.pone.0332345
- Citations
- 2
- Primary Topic
- Potassium and Related Disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.04