Sex differences in the association between visceral adiposity index and biological aging: A cross-sectional analysis of NHANES 1999–2018 with mediation by insulin resistance
VAI showed a significant positive association with BA, with females demonstrating a stronger association strength and males showing a greater proportion of the association mediated through HOMA-IR.
Authors
- Haifeng Liu (ORCID: https://orcid.org/0000-0002-5888-1811)
- Zheng Fu (ORCID: https://orcid.org/0000-0003-2618-2853)
- Jia Yang (ORCID: https://orcid.org/0009-0007-8012-2524)
- Jie Zhou (ORCID: https://orcid.org/0000-0002-6002-291X)
- Weimin Zhao (ORCID: https://orcid.org/0000-0002-2148-3246)
- Xupeng Huang
- Tiejun Liu (ORCID: https://orcid.org/0000-0001-7428-7399)
Institutions
- Changchun University of Chinese Medicine (CN)
- The Affiliated Hospital to Changchun University of Chinese Medicine (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1371/journal.pone.0333472
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00