Safety of Bacillus Calmette-Guérin Vaccination and Impact on HIV-1 Latent Reservoir Size in People With Treated HIV-1 Infection
BCG vaccination is safe in PWH, but local skin reactions including scarring are common. There was no significant effect on the HIV-1 reservoir. These findings provide valuable insights into the safety profile of BCG vaccination in PWH, emphasizing its potential for broader immunological studies.
Authors
- Kathrin Neumann (ORCID: https://orcid.org/0000-0001-5034-6999)
- Johannes Nemeth (ORCID: https://orcid.org/0000-0003-0683-456X)
- Karin J. Metzner (ORCID: https://orcid.org/0000-0003-4862-1503)
- Huldrych F. Günthard (ORCID: https://orcid.org/0000-0002-1142-6723)
- Sandra E Chaudron (ORCID: https://orcid.org/0000-0002-1385-1854)
- Christina Grube
- Roger D. Kouyos (ORCID: https://orcid.org/0000-0002-9220-8348)
- Doris Russenberger
- Dominique L. Braun (ORCID: https://orcid.org/0000-0003-4036-1030)
- Marisa Kälin (ORCID: https://orcid.org/0000-0002-4924-9099)
- Jasmin Tschumi
- Emily West
- Cédric Dollé (ORCID: https://orcid.org/0009-0003-8297-0632)
- Terence K Tutumlu
Institutions
- ZHAW Zurich University of Applied Sciences (CH)
- University of Zurich (CH)
- University Hospital of Zurich (CH)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1093/ofid/ofaf611
- Primary Topic
- Immune responses and vaccinations
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Foundation
- Gilead Sciences
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung