Co-occurrence of Primary Headache and Tremor in a Young Woman: A Case Report

This case report describes a 28-year-old woman presenting with right temporal headache and tremor of the right hand. She had a history of menstrual-related, nonthrobbing headaches but no prior tremors or visual symptoms. Neurological examination revealed a 5-Hz resting and postural tremor in the right upper limb, hyperreflexia, and normal cognitive function, with unremarkable magnetic resonance imaging findings. Blood tests showed euthyroidism and elevated inflammatory and lipid markers. Surface electromyography confirmed the tremor. The patient was diagnosed with tremor associated with primary headache and responded rapidly to clonazepam, with symptom resolution the next day. This case underscores the diagnostic difficulties presented by the atypical co-occurrence of primary headache and tremor. It highlights the importance of considering functional disorders in the differential diagnosis when encountering such presentations, alongside a thorough exclusion of organic causes.

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Publication Details

Journal
Cureus
Published
2025-09-29
DOI
https://doi.org/10.7759/cureus.93509
Primary Topic
Neurological disorders and treatments
Type
article
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article

Co-occurrence of Primary Headache and Tremor in a Young Woman: A Case Report

Yasutaka Kobayashi, Toyoaki Miura, Yuka Nakaya, Kôji Hayashi et al.
Cureus
Neurological disorders and treatments
article

Co-occurrence of Primary Headache and Tremor in a Young Woman: A Case Report

Yasutaka Kobayashi, Toyoaki Miura, Yuka Nakaya, Kôji Hayashi, Mamiko Sato
article en

Abstract

This case report describes a 28-year-old woman presenting with right temporal headache and tremor of the right hand. She had a history of menstrual-related, nonthrobbing headaches but no prior tremors or visual symptoms. Neurological examination revealed a 5-Hz resting and postural tremor in the right upper limb, hyperreflexia, and normal cognitive function, with unremarkable magnetic resonance imaging findings. Blood tests showed euthyroidism and elevated inflammatory and lipid markers. Surface electromyography confirmed the tremor. The patient was diagnosed with tremor associated with primary headache and responded rapidly to clonazepam, with symptom resolution the next day. This case underscores the diagnostic difficulties presented by the atypical co-occurrence of primary headache and tremor. It highlights the importance of considering functional disorders in the differential diagnosis when encountering such presentations, alongside a thorough exclusion of organic causes.

CureusVol. 17(9)
University of Fukui (JP), Fukui University of Technology (JP), University of Fukui Hospital (JP)
Openalex Percentile: Top 62%
Neurological disorders and treatments
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Co-occurrence of Primary Headache and Tremor in a Young Woman: A Case Report — Yasutaka Kobayashi, Toyoaki Miura, et al. · Cureus (2025) | TGRS Research Map | TGRS