Interleukin-27-adipose-derived mesenchymal stromal cell-based gene therapy attenuates inflammation in lipopolysaccharide-induced acute respiratory distress syndrome
Collectively, our in vitro and in vivo results show promising potential for IL-27 cell-based gene therapy as a treatment for ARDS.
Authors
- Grace E. Mulia (ORCID: https://orcid.org/0000-0003-4880-4342)
- Marxa L. Figueiredo (ORCID: https://orcid.org/0000-0002-8134-0749)
- Janelle W. Salameh (ORCID: https://orcid.org/0000-0001-8458-9956)
- Ying-Cheng Chen (ORCID: https://orcid.org/0000-0002-3344-6266)
- Violeta Lardon Galindo
Institutions
- Purdue University West Lafayette (US)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1186/s13287-025-04647-1
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Center for Advancing Translational Sciences