EXPLORING THE DIVERSE BIOMEDICAL APPLICATIONS OF LACTOFERRIN

Lactoferrin, a potential multifunctional glycoprotein that is widely found in milk from mammals and other mucosal secretions, has attracted a lot of interest in biomedical research.The goal of this review is to present a thorough summary of lactoferrin's biological uses, including its function in immunomodulation, antimicrobial activity, anti-inflammatory qualities, and potential future applications in cancer treatment.Studies upon lactoferrin potential in biomedicine were searched from PubMed, Google scholar databases between 2010-2023 and studied.A total of 30 articles emphasizing the chemical and biological properties of lactoferrin were examined.The anticancer effect of lactoferrin has also been studied in different cell lines.Because of its well-established immunomodulatory properties, it has strengthen both innate and adaptive immune responses, lactoferrin is a viable option for enhancing immune system performance and fending off infections.Furthermore, by controlling immune cell activation, reducing inflammatory signalling pathways, and modifying cytokine production, lactoferrin demonstrates anti-inflammatory qualities that point to its potential use as a treatment for inflammatory diseases such sepsis, rheumatoid arthritis etc. Lactoferrin's anticancer potential has also been revealed by recent studies, which clarify how it might prevent the growth of cancer cells, trigger apoptosis, stifle angiogenesis, and improve the effectiveness of traditional cancer treatments.This research works done on various cell lines like Hs578T,