Change in platelet and leukocyte counts and hospital mortality in adults with acute kidney injury receiving continuous renal replacement therapy
In critically ill adults, a drop in platelets after CRRT initiation was associated with increased hospital mortality. Monitoring platelet and WBC during CRRT in reference to pre-CRRT levels could help identify high-risk patients.
Authors
- Lucas J. Liu (ORCID: https://orcid.org/0000-0003-2890-9673)
- Augusto Cama-Olivares (ORCID: https://orcid.org/0000-0002-6588-9475)
- Robert D. Toto (ORCID: https://orcid.org/0000-0001-9531-1749)
- Javier A. Neyra (ORCID: https://orcid.org/0000-0002-2817-2459)
- Chloe G. Braun (ORCID: https://orcid.org/0009-0009-5271-5669)
- Victor Ortiz-Soriano (ORCID: https://orcid.org/0000-0001-8527-6919)
- Orson W. Moe (ORCID: https://orcid.org/0000-0001-9176-3414)
- Lan N. Bui (ORCID: https://orcid.org/0000-0001-9048-8094)
- Ashita Tolwani (ORCID: https://orcid.org/0000-0002-2445-0386)
- Joshua Lambert (ORCID: https://orcid.org/0000-0002-4513-8156)
- KIANOUSH B KASHANI (ORCID: https://orcid.org/0000-0003-2184-3683)
- Jin Chen (ORCID: https://orcid.org/0000-0003-4410-6547)
- Tomonori Takeuchi (ORCID: https://orcid.org/0000-0002-7791-7349)
Institutions
- Mayo Clinic (US)
- University of Kentucky (US)
- University of Alabama at Birmingham (US)
- Southwestern Medical Center (US)
- Brookwood Baptist Health (US)
- Palm Beach Atlantic University (US)
- The University of Texas Southwestern Medical Center (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- Scientific Reports
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1038/s41598-025-18452-6
- Citations
- 2
- Primary Topic
- Acute Kidney Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 2.86
Funders
- American Society of Nephrology
- National Institutes of Health