Evolution from early to difficult-to-treat rheumatoid arthritis: incidence and risk factors in the ERA uclouvain Brussels cohort
Baseline radiographic damage, seropositivity, and high disease activity represent the major risk factors for the evolution from ERA to D2T-RA. Disease activity indices were consistently higher in D2T patients all along the five-year follow-up. In addition, D2T patients received higher GC doses and more commonly developed disease and treatment-related comorbidities.
Authors
- A. Avramovska
- E. Sapart
- S. Dierckx (ORCID: https://orcid.org/0000-0002-9062-679X)
- Clément Triaille (ORCID: https://orcid.org/0000-0001-9227-3820)
- Francesco Natalucci (ORCID: https://orcid.org/0000-0002-9200-1056)
- S. De Montjoye
- Patrick Durez (ORCID: https://orcid.org/0000-0002-7156-2356)
- Cécile Van Mullem
- T. Sokolova (ORCID: https://orcid.org/0000-0003-3148-5672)
Institutions
- Cliniques Universitaires Saint-Luc (BE)
- CHU Dinant Godinne UCL Namur (BE)
- UCLouvain (BE)
Publication Details
- Journal
- Arthritis Research & Therapy
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1186/s13075-025-03645-1
- Citations
- 4
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 6.67