Corticosteroid injection for pyogenic granuloma of the tongue in a rare resembling ulcerative malignancy: a case report

Extragingival PGs in the mouth are relatively rare, and longstanding ulcerative protrusions occurring on the lateral margins of the tongue are often recognized as ulcerative tumors, and pathology is necessary to distinguish malignant tumors from PGs. Trauma, altered hormone levels, and medications can all contribute to the development of PGs, and we hypothesize that the sharp dental cusps, altered estrogen secretion, long-term use of antidepressant medications, and partial gastrointestinal resection may contributed to the development of PG in this woman. The conventional treatment for PG is surgical resection. In this case, good therapeutic effect was achieved after using multi-point topical injection of corticosteroid, combined with wet compress, mouthwash, and medication application, which provides clinical basis for the selection of non-surgical treatment for PG.

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Publication Details

Journal
BMC Oral Health
Published
2025-09-29
DOI
https://doi.org/10.1186/s12903-025-06889-0
Primary Topic
Vascular Malformations and Hemangiomas
Type
article
Field-Weighted Citation Impact
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article

Corticosteroid injection for pyogenic granuloma of the tongue in a rare resembling ulcerative malignancy: a case report

Chuanxia Liu, Qinghua Mao, Y. Zhang, Yinyan Wang et al.
BMC Oral Health
Vascular Malformations and Hemangiomas
article

Corticosteroid injection for pyogenic granuloma of the tongue in a rare resembling ulcerative malignancy: a case report

Chuanxia Liu, Qinghua Mao, Y. Zhang, Yinyan Wang, Fei Sun
article en

Abstract

Extragingival PGs in the mouth are relatively rare, and longstanding ulcerative protrusions occurring on the lateral margins of the tongue are often recognized as ulcerative tumors, and pathology is necessary to distinguish malignant tumors from PGs. Trauma, altered hormone levels, and medications can all contribute to the development of PGs, and we hypothesize that the sharp dental cusps, altered estrogen secretion, long-term use of antidepressant medications, and partial gastrointestinal resection may contributed to the development of PG in this woman. The conventional treatment for PG is surgical resection. In this case, good therapeutic effect was achieved after using multi-point topical injection of corticosteroid, combined with wet compress, mouthwash, and medication application, which provides clinical basis for the selection of non-surgical treatment for PG.

BMC Oral HealthVol. 25(1)
Zhejiang University Medical College Affiliated Stomatological Hospital (CN), Stomatology Hospital (CN), Shaoxing People's Hospital (CN)
Openalex Percentile: Top 57%
Vascular Malformations and Hemangiomas
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