Low-dose rituximab in lupus enteritis: a comparative study on its efficacy in modulating mucosal immunity and reducing inflammation
Both RTX plus glucocorticoids and conventional immunosuppressants plus glucocorticoids are effective in inducing clinical and radiologic remission in LE. RTX may lead to faster improvement in certain serologic and inflammatory biomarkers. Larger studies with longer follow-up and stratification by systemic involvement are warranted to optimize individualized treatment strategies.
Authors
- Wenqin Gao
- Ke Xu (ORCID: https://orcid.org/0000-0003-1458-8741)
- Liangyu Mi
- Yinuo Pang (ORCID: https://orcid.org/0000-0002-9731-5118)
- Na Zhang (ORCID: https://orcid.org/0000-0001-8750-1198)
- Ying Liu (ORCID: https://orcid.org/0000-0002-6540-0473)
- Yang Liu (ORCID: https://orcid.org/0000-0003-0797-4687)
- Yanan Gao (ORCID: https://orcid.org/0009-0003-4478-5946)
Institutions
- Shanxi Academy of Medical Sciences (CN)
Publication Details
- Journal
- Arthritis Research & Therapy
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1186/s13075-025-03653-1
- Citations
- 1
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 1.67