Genomic identification and characterization of Streptococcus oralis group that causes intraamniotic infection
We reported a comprehensive genomic analysis of S. oralis, which causes intraamniotic infection. S. mitis was initially identified by conventional microbiological identification. However, whole-genome hybrid sequencing demonstrates S. oralis with complete profiles of antimicrobial resistance genes and potential virulence factors. This study highlights the limitations of traditional techniques and underscores the importance of genomic sequencing for accurate diagnosis and tailored antimicrobial treatment. The study also suggests that S. oralis may be an underestimated pathogen in intraamniotic infection.
Authors
- Piroon Jenjaroenpun (ORCID: https://orcid.org/0000-0002-1555-401X)
- Worarat Kruasuwan (ORCID: https://orcid.org/0000-0002-0421-0211)
- Iyarit Thaipisuttikul (ORCID: https://orcid.org/0009-0007-0242-0171)
- Thidathip Wongsurawat (ORCID: https://orcid.org/0000-0002-3659-2074)
- Paninee Mongkolsuk
- Arunee Singhsnaeh
- Pornpun Vivithanaporn (ORCID: https://orcid.org/0000-0002-2639-9545)
- Maolee Bhuwapathanapun
- Pisut Pongchaikul (ORCID: https://orcid.org/0000-0001-8757-3554)
- Piya Chaemsaithong (ORCID: https://orcid.org/0000-0003-1750-9834)
- Jakkrit Khamphakul
- Puntabut Warintaksa (ORCID: https://orcid.org/0000-0002-7946-3774)
- Suwatcharaporn Hadradchai
Institutions
- Siriraj Hospital (TH)
- University of Liverpool (GB)
- Mahidol University (TH)
- Ramathibodi Hospital (TH)
Publication Details
- Journal
- European Journal of Clinical Microbiology & Infectious Diseases
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1007/s10096-025-05283-6
- Primary Topic
- Neonatal and Maternal Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Mahidol University