HIV Dolutegravir resistance and multiclass failure in Mozambique: findings from a real-world cohort
This study reports the presence of DTG resistance and multiclass failure in Mozambique, suggesting potential limitations of current strategies. Sentinel surveillance and expanded access to resistance testing are important to preserve the efficacy of DTG-based regimens and inform future deployment of long-acting therapies in sub-Saharan Africa.
Authors
- Fausto Ciccacci (ORCID: https://orcid.org/0000-0003-0262-707X)
- Noorjehan Majid
- Anna Maria Doro Altan
- S. Orlando (ORCID: https://orcid.org/0000-0001-5116-3908)
- Zita Sidumo
- Carlo Federico Perno (ORCID: https://orcid.org/0000-0002-0825-5388)
- Giovanni Guidotti (ORCID: https://orcid.org/0000-0002-8462-2901)
- Margarida Rafael (ORCID: https://orcid.org/0000-0003-0200-2539)
- Paola Germano
- Elton Uamusse
Institutions
- University of Rome Tor Vergata (IT)
- ASL Roma (IT)
- Presidio Ospedaliero (IT)
- Bambino Gesù Children's Hospital (IT)
- Link Campus University (IT)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1186/s12879-025-11639-2
- Citations
- 3
- Primary Topic
- HIV/AIDS drug development and treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.19