Oncologic and survival outcomes of pT2N0 rectal adenocarcinoma treated by transanal local excision: a retrospective cohort study
In selected patients with pT2N0 rectal cancer discovered after transanal excision, adjuvant radiotherapy may provide outcomes comparable to salvage surgery and serve as an alternative in patients not suitable for surgery. High-risk histopathologic features should inform further management, as local excision alone was associated with worse outcomes. Multidisciplinary evaluation remains crucial for treatment planning.
Authors
- Mario Barbiero
- Giovanni Distefano
- Mario Morino (ORCID: https://orcid.org/0000-0003-4540-1409)
- Carlo Alberto Ammirati (ORCID: https://orcid.org/0000-0002-9892-4572)
- Alberto Arezzo (ORCID: https://orcid.org/0000-0002-2110-4082)
- Roberto Passera (ORCID: https://orcid.org/0000-0003-3372-2248)
Institutions
- CTO Hospital (IT)
- Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT)
- Department of Medical Sciences (RU)
Publication Details
- Journal
- Surgical Endoscopy
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1007/s00464-025-12239-6
- Citations
- 1
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- HORIZON EUROPE Framework Programme