Shared and non-overlapping functions of RECQL4 and BLM helicases in chemotherapeutics-induced glioma cell responses
Our results highlight the distinct roles of RecQ helicases in a response to chemotherapeutics and support a rationale for targeting RECQL4 as a therapeutic strategy in glioblastoma.
Authors
- Bartosz Wojtaś (ORCID: https://orcid.org/0000-0002-9967-910X)
- Beata Kaza (ORCID: https://orcid.org/0000-0002-3630-6496)
- Matthew Guille (ORCID: https://orcid.org/0000-0001-6865-4519)
- Kamil Wojnicki (ORCID: https://orcid.org/0000-0002-1630-4389)
- Bożena Kamińska (ORCID: https://orcid.org/0000-0002-2642-4616)
- Waldemar Priebe (ORCID: https://orcid.org/0000-0003-4522-4772)
- Iwona A. Ciechomska (ORCID: https://orcid.org/0000-0002-8068-0020)
Institutions
- The University of Texas MD Anderson Cancer Center (US)
- Instytut Biologii Doświadczalnej im. Marcelego Nenckiego (PL)
- University of Zurich (CH)
- University Children's Hospital Zurich (CH)
- University of Portsmouth (GB)
- Polish Academy of Sciences (PL)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1186/s12885-025-14932-0
- Primary Topic
- DNA Repair Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- Fundacja na rzecz Nauki Polskiej
- European Regional Development Fund