Subacute invasive pulmonary aspergillosis following breast cancer treatment: A one-year diagnostic odyssey

This case illustrates the prolonged diagnostic odyssey characteristic of SIPA in cancer survivors and emphasises the critical importance of maintaining clinical suspicion for invasive fungal infections beyond the immediate post-chemotherapy period. Molecular diagnostics combined with Aspergillus-specific serology proved superior to conventional methods, whilst serial antibody monitoring provided valuable biomarker-guided treatment assessment. Early recognition and appropriate antifungal therapy can achieve excellent outcomes even after protracted symptomatic periods.

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Publication Details

Journal
IDCases
Published
2025-01-01
DOI
https://doi.org/10.1016/j.idcr.2025.e02382
Primary Topic
Antifungal resistance and susceptibility
Type
article
Field-Weighted Citation Impact
0.00
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article

Subacute invasive pulmonary aspergillosis following breast cancer treatment: A one-year diagnostic odyssey

Mohammad Reza Sarveghad, Zahra Sheidae Mehne, Elham Honarjou
IDCases
Antifungal resistance and susceptibility
article

Subacute invasive pulmonary aspergillosis following breast cancer treatment: A one-year diagnostic odyssey

Mohammad Reza Sarveghad, Zahra Sheidae Mehne, Elham Honarjou
article en

Abstract

This case illustrates the prolonged diagnostic odyssey characteristic of SIPA in cancer survivors and emphasises the critical importance of maintaining clinical suspicion for invasive fungal infections beyond the immediate post-chemotherapy period. Molecular diagnostics combined with Aspergillus-specific serology proved superior to conventional methods, whilst serial antibody monitoring provided valuable biomarker-guided treatment assessment. Early recognition and appropriate antifungal therapy can achieve excellent outcomes even after protracted symptomatic periods.

IDCasesVol. 42
Mashhad University of Medical Sciences (IR)
Openalex Percentile: Top 68%
Antifungal resistance and susceptibility
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